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9Z6U

The structure of TMD with 2 TARPs and 2 CNIHs from all native AMPA receptor subtypes

Functional Information from GO Data
ChainGOidnamespacecontents
G0005245molecular_functionvoltage-gated calcium channel activity
G0005246molecular_functioncalcium channel regulator activity
G0005515molecular_functionprotein binding
G0005886cellular_componentplasma membrane
G0014069cellular_componentpostsynaptic density
G0016247molecular_functionchannel regulator activity
G0019226biological_processtransmission of nerve impulse
G0030346molecular_functionprotein phosphatase 2B binding
G0032281cellular_componentAMPA glutamate receptor complex
G0032590cellular_componentdendrite membrane
G0035255molecular_functionionotropic glutamate receptor binding
G0045202cellular_componentsynapse
G0045211cellular_componentpostsynaptic membrane
G0051968biological_processpositive regulation of synaptic transmission, glutamatergic
G0070588biological_processcalcium ion transmembrane transport
G0098685cellular_componentSchaffer collateral - CA1 synapse
G0098839cellular_componentpostsynaptic density membrane
G0098970biological_processpostsynaptic neurotransmitter receptor diffusion trapping
G0098978cellular_componentglutamatergic synapse
G0099072biological_processregulation of postsynaptic membrane neurotransmitter receptor levels
G1990454cellular_componentL-type voltage-gated calcium channel complex
G2000311biological_processregulation of AMPA receptor activity
G2000969biological_processpositive regulation of AMPA receptor activity
H0005245molecular_functionvoltage-gated calcium channel activity
H0005246molecular_functioncalcium channel regulator activity
H0005515molecular_functionprotein binding
H0005886cellular_componentplasma membrane
H0014069cellular_componentpostsynaptic density
H0016247molecular_functionchannel regulator activity
H0019226biological_processtransmission of nerve impulse
H0030346molecular_functionprotein phosphatase 2B binding
H0032281cellular_componentAMPA glutamate receptor complex
H0032590cellular_componentdendrite membrane
H0035255molecular_functionionotropic glutamate receptor binding
H0045202cellular_componentsynapse
H0045211cellular_componentpostsynaptic membrane
H0051968biological_processpositive regulation of synaptic transmission, glutamatergic
H0070588biological_processcalcium ion transmembrane transport
H0098685cellular_componentSchaffer collateral - CA1 synapse
H0098839cellular_componentpostsynaptic density membrane
H0098970biological_processpostsynaptic neurotransmitter receptor diffusion trapping
H0098978cellular_componentglutamatergic synapse
H0099072biological_processregulation of postsynaptic membrane neurotransmitter receptor levels
H1990454cellular_componentL-type voltage-gated calcium channel complex
H2000311biological_processregulation of AMPA receptor activity
H2000969biological_processpositive regulation of AMPA receptor activity
Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues40
DetailsTransmembrane: {"description":"Helical","evidences":[{"evidenceCode":"ECO:0000250"}]}
ChainResidueDetails

site_idSWS_FT_FI2
Number of Residues160
DetailsTransmembrane: {"description":"Helical","evidences":[{"evidenceCode":"ECO:0000255"}]}
ChainResidueDetails

251174

PDB entries from 2026-03-25

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