9Z6T

Human HCN1 in complex with cAMP in nanodisc

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1,Thermostable Green Protein	polymer	906	103035.6	4	UniProt (O60741)	Homo sapiens (human)
2	E, F, G, H (A, B, C, D)	ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE	non-polymer		329.2	4	Chemie (CMP) PubChem (23902375) PubChem (25322948) PubChem (176488666) PubChem (25322946) PubChem (40467852) PubChem (59350541) PubChem (44629928) PubChem (274) PubChem (6604194) PubChem (56973690) PubChem (163043517) PubChem (59909322) PubChem (59968988) PubChem (70878457) PubChem (6076) PubChem (124132380) PubChem (216878) PubChem (3080770) PubChem (3246347) PubChem (6603718) PubChem (6713792) PubChem (6714006) PubChem (129317551) PubChem (12071879) PubChem (12866365) PubChem (131841987) PubChem (134693155) PubChem (138107790) PubChem (163043518)

Sequence modifications

A, B, C, D: 2 - 635 (UniProt: O60741)

PDB	External Database	Details
Met -9	-	initiating methionine
Asp -8	-	expression tag
Tyr -7	-	expression tag
Lys -6	-	expression tag
Asp -5	-	expression tag
Asp -4	-	expression tag
Asp -3	-	expression tag
Asp -2	-	expression tag
Lys -1	-	expression tag
Gly 0	-	expression tag
Ser 1	-	expression tag

A, B, C, D: 636 - 896 (PDB: 9Z6T)

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	412142.4
Non-Polymers*	Number of molecules	4
	Total formula weight	1316.8
All*	Total formula weight	413459.2

*Water molecules are not included.