9YND
Motor domain of human dynein-1 in pre-power stroke bound to dynactin-p150glued-CC1B and LIS1
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Cytoplasmic dynein 1 heavy chain 1 | polymer | 4646 | 533083.3 | 1 | UniProt (Q14204) | Homo sapiens (human) | Cytoplasmic dynein heavy chain 1,Dynein heavy chain,cytosolic |
| 2 | B, C, D, E (B, C, D, E) | Platelet-activating factor acetylhydrolase IB subunit beta | polymer | 410 | 46710.0 | 4 | UniProt (P43034) | Homo sapiens (human) | Lissencephaly-1 protein,LIS-1,PAF acetylhydrolase 45 kDa subunit,PAF-AH 45 kDa subunit,PAF-AH alpha,PAFAH alpha |
| 3 | F, G (F, G) | Cytoplasmic dynein 1 intermediate chain 2 | polymer | 638 | 71546.4 | 2 | UniProt (Q13409) | Homo sapiens (human) | Cytoplasmic dynein intermediate chain 2,Dynein intermediate chain 2,cytosolic,DH IC-2 |
| 4 | H, I (H, I) | Dynactin subunit 1 | polymer | 1281 | 142015.5 | 2 | UniProt (Q14203) | Homo sapiens (human) | 150 kDa dynein-associated polypeptide,DAP-150,DP-150,p135,p150-glued |
| 5 | J, L, M (A) | ADENOSINE-5'-DIPHOSPHATE | non-polymer | 427.2 | 3 | Chemie (ADP) | |||
| 6 | K (A) | ADENOSINE-5'-TRIPHOSPHATE | non-polymer | 507.2 | 1 | Chemie (ATP) | |||
| 7 | N, O (A) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) |
Sequence modifications
H, I: 1 - 1281 (UniProt: Q14203)
| PDB | External Database | Details |
|---|---|---|
| Arg 118 | Lys 118 | conflict |
| Ser 124 | Thr 124 | conflict |
| Asn 125 | Thr 125 | conflict |
| Pro 134 | Leu 134 | conflict |
| Ala 200 | Val 200 | conflict |
| Ala 207 | Val 207 | conflict |
| Asp 631 | Glu 631 | conflict |
| Ser 742 | Cys 742 | conflict |
| Ser 778 | Thr 778 | conflict |
| Ala 821 | Pro 821 | conflict |
| Pro 862 | Leu 862 | conflict |
| Ile 1048 | Leu 1048 | conflict |
| Gly 1072 | Ala 1072 | conflict |
| Ala 1073 | Ile 1073 | conflict |
| Ile 1080 | Ser 1080 | conflict |
| Val 1113 | Ile 1113 | conflict |
| Ala 1125 | Ser 1125 | conflict |
| Leu 1136 | - | insertion |
| Pro 1137 | - | insertion |
| Pro 1138 | - | insertion |
| Ala 1147 | Pro 1144 | conflict |
| Asn 1156 | Ser 1153 | conflict |
| Ser 1177 | Thr 1174 | conflict |
| Leu 1189 | Met 1186 | conflict |
| Thr 1193 | Ala 1190 | conflict |
| Ile 1202 | Val 1199 | conflict |
| Leu 1259 | Phe 1256 | conflict |
| Asp 1277 | Ser 1274 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 9 |
| Total formula weight | 1147047.0 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 1837.4 | |
| All* | Total formula weight | 1148884.4 |
