9YHR
AJ09-110 Fab in complex with HIV-1 Env 5MUT-3fill SOSIP
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | Transmembrane protein gp41 | polymer | 153 | 17134.3 | 3 | UniProt (Q2N0S6) | Human immunodeficiency virus 1 (HIV-1) | TM, Glycoprotein 41, gp41 |
| 2 | D, E, F (E, F, G) | Envelope glycoprotein gp120 | polymer | 479 | 53927.0 | 3 | UniProt (Q2N0S6) | Human immunodeficiency virus 1 (HIV-1) | Env polyprotein |
| 3 | G, H, K (H, J, M) | AJ09-110 Fab heavy chain | polymer | 125 | 13778.2 | 3 | Human immunodeficiency virus 1 (HIV-1) | ||
| 4 | I, J, L (K, L, N) | AJ09-110 Fab light chain | polymer | 112 | 12299.7 | 3 | Macaca mulatta (Rhesus monkey) | ||
| 5 | AA, M, O, Q, R... (a, D, O, Q, R...) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 9 | In PDB GlyTouCan (G42666HT) | |||
| 6 | N, S, X (I, S, X) | alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 748.7 | 3 | In PDB GlyTouCan (G81315DD) | |||
| 7 | P, U, Z (P, U, Z) | alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 1235.1 | 3 | In PDB GlyTouCan (G46836GH) | |||
| 8 | AB, BA, BB, CA, CB... (F, A, B, C, E...) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 42 | Chemie (NAG) PubChem (24139) |
Sequence modifications
A, B, C: 512 - 664 (UniProt: Q2N0S6)
E, F, G: 33 - 513 (UniProt: Q2N0S6)
| PDB | External Database | Details |
|---|---|---|
| Ser 519 | Phe 516 | conflict |
| Pro 559 | Ile 556 | conflict |
| Pro 561 | Ala 558 | conflict |
| Asp 568 | Leu 565 | conflict |
| His 570 | Val 567 | conflict |
| His 585 | Arg 582 | conflict |
| Cys 605 | Thr 602 | conflict |
| PDB | External Database | Details |
|---|---|---|
| Glu 106 | Thr 105 | conflict |
| Tyr 134 | Val 133 | conflict |
| Pro 136 | Asn 135 | conflict |
| Leu 138 | Ile 137 | conflict |
| Asn 140 | Asp 139 | conflict |
| Cys 201 | Ile 200 | conflict |
| Asn 230 | Asp 229 | conflict |
| Thr 232 | Lys 231 | conflict |
| Asn 241 | Ser 240 | conflict |
| Ile 271 | Met 270 | conflict |
| Leu 288 | Phe 287 | conflict |
| Val 304 | Arg 303 | conflict |
| Tyr 319 | Ala 316 | conflict |
| Asn 332 | Thr 330 | conflict |
| Asn 344 | Lys 342 | conflict |
| Ser 346 | Val 344 | conflict |
| Gln 363 | Asn 361 | conflict |
| Cys 433 | Ala 430 | conflict |
| Cys 501 | Ala 498 | conflict |
| Arg 509 | Glu 506 | conflict |
| Arg 510 | Lys 507 | conflict |
| Arg 512 | Ala 509 | conflict |
| Arg 513 | Val 510 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 12 |
| Total formula weight | 291417.7 | |
| Branched | Number of molecules | 15 |
| Total formula weight | 9771.0 | |
| Non-Polymers* | Number of molecules | 42 |
| Total formula weight | 9290.7 | |
| All* | Total formula weight | 310479.4 |
