9YCL
Cryo-EM structure of MERS-CoV nsp10-nsp14 (E191A) in complex with T20P15 RNA, dimeric form
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, D) | Replicase polyprotein 1ab | polymer | 140 | 14902.9 | 2 | UniProt (K9N7C7) Pfam (PF09401) | Middle East respiratory syndrome-related coronavirus | pp1ab,ORF1ab polyprotein |
| 2 | C, E (B, E) | Guanine-N7 methyltransferase nsp14 | polymer | 524 | 59190.2 | 2 | UniProt (K9N7C7) Pfam (PF06471) | Middle East respiratory syndrome-related coronavirus | ExoN,nsp14 |
| 3 | D, F (C, F) | T20P15 RNA | polymer | 39 | 12478.4 | 2 | Middle East respiratory syndrome-related coronavirus | ||
| 4 | G, H, I, J, L... (A, D, B, E) | ZINC ION | non-polymer | 65.4 | 10 | Chemie (ZN) | |||
| 5 | K, O (B, E) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) |
Sequence modifications
B, E: 1 - 524 (UniProt: K9N7C7)
| PDB | External Database | Details |
|---|---|---|
| Ala 191 | Glu 6099 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 173143.0 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 702.7 | |
| All* | Total formula weight | 173845.7 |
