9YCL
Cryo-EM structure of MERS-CoV nsp10-nsp14 (E191A) in complex with T20P15 RNA, dimeric form
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003723 | molecular_function | RNA binding |
| A | 0008270 | molecular_function | zinc ion binding |
| A | 0019079 | biological_process | viral genome replication |
| B | 0000175 | molecular_function | 3'-5'-RNA exonuclease activity |
| B | 0004482 | molecular_function | mRNA 5'-cap (guanine-N7-)-methyltransferase activity |
| B | 0004532 | molecular_function | RNA exonuclease activity |
| B | 0008168 | molecular_function | methyltransferase activity |
| D | 0003723 | molecular_function | RNA binding |
| D | 0008270 | molecular_function | zinc ion binding |
| D | 0019079 | biological_process | viral genome replication |
| E | 0000175 | molecular_function | 3'-5'-RNA exonuclease activity |
| E | 0004482 | molecular_function | mRNA 5'-cap (guanine-N7-)-methyltransferase activity |
| E | 0004532 | molecular_function | RNA exonuclease activity |
| E | 0008168 | molecular_function | methyltransferase activity |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 58 |
| Details | Zinc finger: {} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 16 |
| Details | Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU01297","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 430 |
| Details | Domain: {"description":"ExoN","evidences":[{"source":"PROSITE-ProRule","id":"PRU01298","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 28 |
| Details | Region: {"description":"GpppA-binding","evidences":[{"source":"PROSITE-ProRule","id":"PRU01299","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 10 |
| Details | Active site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU01298","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 16 |
| Details | Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU01298","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI7 |
| Number of Residues | 20 |
| Details | Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU01299","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
