9YCD
Leucine Rich Repeat Kinase 2 R1441C mutant (active)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Leucine-rich repeat serine/threonine-protein kinase 2 | polymer | 2527 | 286408.7 | 1 | UniProt (Q5S007) | Homo sapiens (human) | Dardarin |
| 2 | B (A) | (2~{R},6~{S})-2,6-dimethyl-4-[6-[5-(1-methylcyclopropyl)oxy-1~{H}-indazol-3-yl]pyrimidin-4-yl]morpholine | non-polymer | 379.5 | 1 | Chemie (A1N) |
Sequence modifications
A: 1 - 2527 (UniProt: Q5S007)
| PDB | External Database | Details |
|---|---|---|
| Cys 1441 | Arg 1441 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 286408.7 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 379.5 | |
| All* | Total formula weight | 286788.2 |
