9Y80

Homomeric Glycine Receptor alpha2 with PTX in a Desensitized State

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E (A, B, C, D, E)	Glycine receptor subunit alpha-2	polymer	466	53782.8	5	UniProt (P23416)	Homo sapiens (human)
2	F, G, GA, HA, M... (A, E, B, C, D)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	10	Chemie (NAG)
3	AA, FA, H, O, U (D, E, A, B, C)	GLYCINE	non-polymer		75.1	5	Chemie (GLY)
4	I (A)	(1aR,2aR,3S,6R,6aS,8aS,8bR,9R)-2a-hydroxy-8b-methyl-9-(prop-1-en-2-yl)hexahydro-3,6-methano-1,5,7-trioxacyclopenta[ij]c yclopropa[a]azulene-4,8(3H)-dione	non-polymer		292.3	1	Chemie (RI5)
5	BA, CA, DA, EA, IA... (D, E, A, B, C)	1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE	non-polymer		678.9	15	Chemie (PX4)

Sequence modifications

A, B, C, D, E: 1 - 452 (UniProt: P23416)

PDB	External Database	Details
Leu 453	-	expression tag
Val 454	-	expression tag
Pro 455	-	expression tag
Arg 456	-	expression tag
Gly 457	-	expression tag
Ser 458	-	expression tag
His 459	-	expression tag
His 460	-	expression tag
His 461	-	expression tag
His 462	-	expression tag
His 463	-	expression tag
His 464	-	expression tag
His 465	-	expression tag
His 466	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	5
	Total formula weight	268914.2
Non-Polymers*	Number of molecules	31
	Total formula weight	13063.8
All*	Total formula weight	281978.0

*Water molecules are not included.