9Y7T
Crystal structure of Candida auris dihydrofolate reductase in complex with inhibitor 1172 and NADPH
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Dihydrofolate reductase | polymer | 204 | 23634.1 | 2 | UniProt (A0A0L0P1H8) | Candidozyma auris | |
| 2 | C, I (A, B) | NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | non-polymer | 745.4 | 2 | Chemie (NDP) | |||
| 3 | D, J (A, B) | 3'-[(2R)-4-(2,4-diamino-6-ethylpyrimidin-5-yl)but-3-yn-2-yl]-5'-methoxy[1,1'-biphenyl]-4-carboxylic acid | non-polymer | 416.5 | 2 | Chemie (G6Y) PubChem (124081251) | |||
| 4 | E, F, K (A, B) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 3 | Chemie (EDO) | |||
| 5 | G, H, L (A, B) | SULFATE ION | non-polymer | 96.1 | 3 | Chemie (SO4) | |||
| 6 | M, N (A, B) | water | water | 18.0 | 191 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 47268.3 | |
| Non-Polymers* | Number of molecules | 10 |
| Total formula weight | 2798.2 | |
| All* | Total formula weight | 50066.5 |
