9Y7Q
Crystal structure of Candida auris dihydrofolate reductase in complex with inhibitor 1051 (S-form) and NADPH
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Dihydrofolate reductase | polymer | 208 | 24047.6 | 2 | UniProt (A0A0L0P1H8) | Candidozyma auris | |
| 2 | C, F (A, B) | NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | non-polymer | 745.4 | 2 | Chemie (NDP) | |||
| 3 | D, E (A, B) | 6-ethyl-5-[(3S)-3-(6-phenylpyridin-3-yl)but-1-yn-1-yl]pyrimidine-2,4-diamine | non-polymer | 343.4 | 2 | Chemie (A1CTC) | |||
| 4 | G, H (A, B) | water | water | 18.0 | 41 | Chemie (HOH) |
Sequence modifications
A, B: 0 - 203 (UniProt: A0A0L0P1H8)
| PDB | External Database | Details |
|---|---|---|
| Gly -4 | - | expression tag |
| Ser -3 | - | expression tag |
| His -2 | - | expression tag |
| Met -1 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 48095.2 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 2177.7 | |
| All* | Total formula weight | 50272.9 |
