9Y4C
Strand displacement state I of Human mitochondrial DNA polymerase gamma ternary complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | DNA polymerase subunit gamma-1 | polymer | 1239 | 139628.7 | 1 | UniProt (P54098) Pfam (PF18136) | Homo sapiens (human) | Mitochondrial DNA polymerase catalytic subunit,PolG-alpha |
| 2 | B, C (B, C) | DNA polymerase subunit gamma-2, mitochondrial | polymer | 485 | 54991.0 | 2 | UniProt (Q9UHN1) Pfam (PF03129) | Homo sapiens (human) | DNA polymerase gamma accessory 55 kDa subunit,p55,Mitochondrial DNA polymerase accessory subunit,MtPolB,PolG-beta |
| 3 | D (D) | DNA (59-MER) | polymer | 77 | 23807.1 | 1 | synthetic construct | ||
| 4 | E (A) | CALCIUM ION | non-polymer | 40.1 | 1 | Chemie (CA) | |||
| 5 | F (A) | 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE | non-polymer | 491.2 | 1 | Chemie (DTP) |
Sequence modifications
A: 1 - 1239 (UniProt: P54098)
| PDB | External Database | Details |
|---|---|---|
| Ala 198 | Asp 198 | engineered mutation |
| Ala 200 | Glu 200 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 273417.8 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 531.3 | |
| All* | Total formula weight | 273949.1 |
