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9Y1M

Cryo EM Structure of Full Length mGluR8 in Complex with Beta-Arrestin-1 Bound to Agonist L-AP4 and PAM VU6005649

This is a non-PDB format compatible entry.
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
Metabotropic glutamate receptor 8polymer908101858.42UniProt (O00222)Homo sapiens (human)mGluR8
2C, E
(A, B)
(2S)-2-amino-4-phosphonobutanoic acidnon-polymer183.12Chemie (E7P)
PubChem (179394)
3D
(B)
(3P,8S)-3-(2,3-difluoro-4-methoxyphenyl)-2,5-dimethyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidinenon-polymer357.31Chemie (A1BWG)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight203716.8
Non-Polymers*Number of molecules3
Total formula weight723.5
All*Total formula weight204440.3
*Water molecules are not included.

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PDB entries from 2026-09-30

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