9XBU

Crystal structure of human SIRT5 in XR-0931

This is a non-PDB format compatible entry.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	NAD-dependent protein deacylase sirtuin-5, mitochondrial	polymer	269	29282.4	2	UniProt (Q9NXA8) Pfam (PF02146)	Homo sapiens (human)	Regulatory protein SIR2 homolog 5,SIR2-like protein 5
2	C, E (A, B)	ZINC ION	non-polymer		65.4	2	Chemie (ZN) PubChem (32051)
3	D, F (A, B)	3-[[(~{Z})-~{N}'-cyano-~{N}-[3-[[2-(6-ethoxypyridin-3-yl)-5-[[4-(trifluoromethyloxy)phenyl]methylcarbamoyl]pyrimidin-4-yl]amino]propyl]carbamimidoyl]amino]propanoic acid	non-polymer		629.6	2	Chemie (A1EZQ)
4	G, H (A, B)	water	water		18.0	183	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	58564.8
Non-Polymers*	Number of molecules	4
	Total formula weight	1390.0
All*	Total formula weight	59954.8

*Water molecules are not included.