9X4F

Crystal structure of tetrameric alpha-enolase with asymmetric flexible active sites

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	Alpha-enolase	polymer	447	48800.7	4	UniProt (P06733) Pfam (PF03952) Pfam (PF00113)	Homo sapiens (human)	2-phospho-D-glycerate hydro-lyase,C-myc promoter-binding protein,Enolase 1,MBP-1,MPB-1,Non-neural enolase,NNE,Phosphopyruvate hydratase,Plasminogen-binding protein
2	E, F, G, H, I... (A, B, C, D)	MAGNESIUM ION	non-polymer		24.3	8	Chemie (MG) PubChem (888)
3	M, N, O, P (A, B, C, D)	water	water		18.0	395	Chemie (HOH)

Sequence modifications

A, B, C, D: 1 - 434 (UniProt: P06733)

PDB	External Database	Details
Met -13	-	initiating methionine
His -12	-	expression tag
His -11	-	expression tag
His -10	-	expression tag
His -9	-	expression tag
His -8	-	expression tag
His -7	-	expression tag
Leu -6	-	expression tag
Val -5	-	expression tag
Pro -4	-	expression tag
Arg -3	-	expression tag
Gly -2	-	expression tag
Ser -1	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	195202.6
Non-Polymers*	Number of molecules	8
	Total formula weight	194.4
All*	Total formula weight	195397.1

*Water molecules are not included.