9X1H
Cryo-EM Structure of human complement C1s CUB domain in complex with RAY121
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (L, M) | RAY121 Fab Light chain | polymer | 220 | 24034.6 | 2 | Homo sapiens (human) | ||
| 2 | C, E (I, H) | RAY121 Fab Heavy chain | polymer | 225 | 24044.9 | 2 | Homo sapiens (human) | ||
| 3 | D, F (B, A) | Complement C1s subcomponent heavy chain | polymer | 290 | 32556.8 | 2 | UniProt (P09871) | Homo sapiens (human) | Complement C1s subcomponent chain A |
| 4 | G, H, I, J (B, A) | CALCIUM ION | non-polymer | 40.1 | 4 | Chemie (CA) |
Sequence modifications
B, A: 1 - 277 (UniProt: P09871)
| PDB | External Database | Details |
|---|---|---|
| Gly 278 | - | expression tag |
| Gly 279 | - | expression tag |
| Gly 280 | - | expression tag |
| Gly 281 | - | expression tag |
| Ser 282 | - | expression tag |
| Asp 283 | - | expression tag |
| Tyr 284 | - | expression tag |
| Lys 285 | - | expression tag |
| Asp 286 | - | expression tag |
| Asp 287 | - | expression tag |
| Asp 288 | - | expression tag |
| Asp 289 | - | expression tag |
| Lys 290 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 161272.7 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 160.3 | |
| All* | Total formula weight | 161433.0 |
