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9WXV

Cryo-EM structure of TMEM63A-digitonin-cholesterol

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Mechanosensitive cation channel TMEM63Apolymer81292743.41UniProt (O94886)Homo sapiens (human)Transmembrane protein 63A,hTMEM63A
2B, C
(A)
CHOLESTEROLnon-polymer386.72Chemie (CLR)
Sequence modifications
A: 1 - 807 (UniProt: O94886)
PDBExternal DatabaseDetails
Ser 808-expression tag
Asn 809-expression tag
Ser 810-expression tag
Leu 811-expression tag
Glu 812-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight92743.4
Non-Polymers*Number of molecules2
Total formula weight773.3
All*Total formula weight93516.7
*Water molecules are not included.

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PDB entries from 2026-02-11

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