9WQN

GRM1-Gq Complex Structure

This is a non-PDB format compatible entry.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (X, Y)	Metabotropic glutamate receptor 1	polymer	869	97322.3	2	UniProt (Q13255)	Homo sapiens (human)	mGluR1
2	C (A)	miniGq	polymer	246	28084.8	1		Homo sapiens (human)
3	D (B)	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1	polymer	340	37416.9	1	UniProt (P62873)	Homo sapiens (human)	Transducin beta chain 1
4	E (G)	Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2	polymer	80	8506.8	1	UniProt (P59768)	Homo sapiens (human)	G gamma-I
5	F (F)	scFv16	polymer	260	27720.8	1		Mus musculus
6	G, R (X, Y)	GAMMA-L-GLUTAMIC ACID	non-polymer		147.1	2	Chemie (GGL)
7	H, I, J, K, S... (X, Y)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	8	Chemie (NAG) PubChem (24139)
8	L, W (X, Y)	CHLORIDE ION	non-polymer		35.5	2	Chemie (CL) PubChem (312)
9	M, N, O, Q, X... (X, Y)	CHOLESTEROL	non-polymer		386.7	7	Chemie (CLR) PubChem (5997)
10	P (X)	N-[4-(trifluoromethyl)-1,3-oxazol-2-yl]-9H-xanthene-9-carboxamide	non-polymer		360.3	1	Chemie (A1EX5)

Sequence modifications

X, Y: 31 - 890 (UniProt: Q13255)

PDB	External Database	Details
Asp 22	-	expression tag
Tyr 23	-	expression tag
Lys 24	-	expression tag
Asp 25	-	expression tag
Asp 26	-	expression tag
Asp 27	-	expression tag
Asp 28	-	expression tag
Lys 29	-	expression tag
Thr 30	-	expression tag

G: 1 - 71 (UniProt: P59768)

PDB	External Database	Details
Gly 72	-	expression tag
Ser 73	-	expression tag
Ala 74	-	expression tag
Gly 75	-	expression tag
Ser 76	-	expression tag
Ala 77	-	expression tag
Gly 78	-	expression tag
Ser 79	-	expression tag
Ala 80	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	296374.0
Non-Polymers*	Number of molecules	20
	Total formula weight	5201.7
All*	Total formula weight	301575.7

*Water molecules are not included.