9WPE

Cryo-EM structure of the insect sex pheromone receptor ApisOR22-Orco heterocomplex bound with nepetalactone in the closed state.

This is a non-PDB format compatible entry.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Odorant receptor	polymer	445	50506.8	1	UniProt (A0A8R2JM50)	Acyrthosiphon pisum (pea aphid)	OR22
2	B, C, D (B, C, D)	Odorant receptor	polymer	463	52916.8	3	UniProt (A0A1S6J137)	Acyrthosiphon pisum (pea aphid)
3	E (A)	(4~{a}~{S},7~{S},7~{a}~{R})-4,7-dimethyl-5,6,7,7~{a}-tetrahydro-4~{a}~{H}-cyclopenta[c]pyran-1-one	non-polymer		166.2	1	Chemie (A1EX6)
4	F, G, H, I, J... (A, B, C, D)	1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE	non-polymer		790.1	6	Chemie (PC1)

Sequence modifications

A: 17 - 445 (UniProt: A0A8R2JM50)

PDB	External Database	Details
Met 1	-	initiating methionine
Lys 2	-	expression tag
Asp 3	-	expression tag
Ile 4	-	expression tag
Leu 5	-	expression tag
Leu 6	-	expression tag
Asn 7	-	expression tag
Ser 8	-	expression tag
Ile 9	-	expression tag
Met 10	-	expression tag
His 11	-	expression tag
Arg 12	-	expression tag
Asn 13	-	expression tag
Asp 14	-	expression tag
Ser 15	-	expression tag
Trp 16	-	expression tag
Gly 33	Val 18	conflict
Gln 50	Lys 35	conflict
Met 243	Ile 228	conflict
Glu 427	Ala 412	conflict

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	209257.1
Non-Polymers*	Number of molecules	7
	Total formula weight	4907.1
All*	Total formula weight	214164.2

*Water molecules are not included.