9WH9

Crystal Structure of Bovine STING bound to diABZI3

This is a non-PDB format compatible entry.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Stimulator of interferon genes protein	polymer	195	22249.0	2	UniProt (Q2KI99)	Bos taurus (domestic cattle)	STING,Transmembrane protein 173
2	C (B)	1-[(2E)-4-{5-carbamoyl-2-[(1-ethyl-3-methyl-1H-pyrazole-5-carbonyl)amino]-7-methoxy-1H-1,3-benzimidazol-1-yl}but-2-en-1-yl]-2-[(1-ethyl-3-methyl-1H-pyrazole-5-carbonyl)amino]-7-[3-(morpholin-4-yl)propoxy]-1H-1,3-benzimidazole-5-carboxamide	non-polymer		849.9	1	Chemie (A1AZ0)
3	D, E (A, B)	water	water		18.0	124	Chemie (HOH)

Sequence modifications

A, B: 155 - 340 (UniProt: Q2KI99)

PDB	External Database	Details
Met 154	-	initiating methionine
Leu 341	-	expression tag
Glu 342	-	expression tag
His 343	-	expression tag
His 344	-	expression tag
His 345	-	expression tag
His 346	-	expression tag
His 347	-	expression tag
His 348	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	44498.1
Non-Polymers*	Number of molecules	1
	Total formula weight	849.9
All*	Total formula weight	45348.0

*Water molecules are not included.