9WH8

Crystal Structure of Human STING bound to diABZI3

This is a non-PDB format compatible entry.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (B)	Stimulator of interferon genes protein	polymer	188	21543.2	1	UniProt (Q86WV6) Pfam (PF15009)	Homo sapiens (human)	hSTING,Endoplasmic reticulum interferon stimulator,ERIS,Mediator of IRF3 activation,hMITA,Transmembrane protein 173
2	B (B)	1-[(2E)-4-{5-carbamoyl-2-[(1-ethyl-3-methyl-1H-pyrazole-5-carbonyl)amino]-7-methoxy-1H-1,3-benzimidazol-1-yl}but-2-en-1-yl]-2-[(1-ethyl-3-methyl-1H-pyrazole-5-carbonyl)amino]-7-[3-(morpholin-4-yl)propoxy]-1H-1,3-benzimidazole-5-carboxamide	non-polymer		849.9	1	Chemie (A1AZ0) PubChem (131986624)
3	C (B)	water	water		18.0	94	Chemie (HOH)

Sequence modifications

B: 154 - 341 (UniProt: Q86WV6)

PDB	External Database	Details
Ser 154	Asn 154	variant
Arg 232	His 232	variant

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	21543.2
Non-Polymers*	Number of molecules	1
	Total formula weight	849.9
All*	Total formula weight	22393.1

*Water molecules are not included.