9WH8

Crystal Structure of Human STING bound to diABZI3

This is a non-PDB format compatible entry.

Experimental procedure

Experimental method	SINGLE WAVELENGTH
Source type	SYNCHROTRON
Source details	APS BEAMLINE 21-ID-D
Synchrotron site	APS
Beamline	21-ID-D
Temperature [K]	100
Detector technology	PIXEL
Collection date	2025-04-12
Detector	DECTRIS EIGER2 S 9M
Wavelength(s)	0.97918
Spacegroup name	P 61 2 2
Unit cell lengths	62.763, 62.763, 219.376
Unit cell angles	90.00, 90.00, 120.00

Refinement procedure

Resolution	34.140 - 1.900
R-factor	0.2121
Rwork	0.210
R-free	0.26250
Structure solution method	MOLECULAR REPLACEMENT
Data reduction software	DIALS
Data scaling software	DIALS
Phasing software	PHENIX
Refinement software	PHENIX (1.17.1_3660)

Data quality characteristics

	Overall	Outer shell
Low resolution limit [Å]	219.380	1.950
High resolution limit [Å]	1.900	1.900
Number of reflections	21256	1504
<I/σ(I)>	21.5
Completeness [%]	100.0
Redundancy	36.6
CC(1/2)	1.000	0.875

Crystallization Conditions

crystal ID	method	pH	temperature	details
1	VAPOR DIFFUSION, HANGING DROP		277	0.1M Imidazole pH6.5, 1M Sodium acetate trihydrate