9WBD
Crystal structure of HLA-B*07:02 in complex with SPR epitope and Q04 TCR
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, F, K, P (A, F, K, P) | T cell receptor alpha variable 25,T cell receptor alpha chain constant | polymer | 206 | 23105.7 | 4 | UniProt (A0A0B4J276) UniProt (P01848) Pfam (PF07686) Pfam (PF09291) | Homo sapiens (human) | |
| 2 | B, G, L, Q (B, G, L, Q) | TCR beta | polymer | 243 | 27205.2 | 4 | Homo sapiens | ||
| 3 | C, H, M, R (C, H, M, R) | HLA class I histocompatibility antigen, B alpha chain | polymer | 276 | 32093.2 | 4 | UniProt (P01889) Pfam (PF00129) Pfam (PF07654) | Homo sapiens (human) | Human leukocyte antigen B,HLA-B |
| 4 | D, I, N, S (D, I, N, S) | Beta-2-microglobulin | polymer | 100 | 11879.4 | 4 | UniProt (P61769) Pfam (PF07654) | Homo sapiens (human) | |
| 5 | E, J, O, T (E, J, O, T) | Nucleoprotein | polymer | 9 | 1295.5 | 4 | UniProt (P0DTC9) | Severe acute respiratory syndrome coronavirus 2 | SER-PRO-ARG-TRP-TYR-PHE-TYR-TYR-LEU,N,Nucleocapsid protein,NC,Protein N |
| 6 | U, W, X (B, L, Q) | GLYCEROL | non-polymer | 92.1 | 3 | Chemie (GOL) | |||
| 7 | V (G) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 1 | Chemie (PEG) | |||
| 8 | AA, BA, Y, Z (M, R, C, H) | water | water | 18.0 | 14 | Chemie (HOH) |
Sequence modifications
A, F, K, P: 2 - 92 (UniProt: A0A0B4J276)
A, F, K, P: 114 - 206 (UniProt: P01848)
C, H, M, R: 1 - 275 (UniProt: P01889)
D, I, N, S: 1 - 99 (UniProt: P61769)
| PDB | External Database | Details |
|---|---|---|
| Met 1 | - | initiating methionine |
| Tyr 93 | - | linker |
| Thr 94 | - | linker |
| Ser 95 | - | linker |
| Gly 96 | - | linker |
| Thr 97 | - | linker |
| Tyr 98 | - | linker |
| Lys 99 | - | linker |
| Tyr 100 | - | linker |
| Ile 101 | - | linker |
| Phe 102 | - | linker |
| Gly 103 | - | linker |
| Thr 104 | - | linker |
| Gly 105 | - | linker |
| Thr 106 | - | linker |
| Arg 107 | - | linker |
| Leu 108 | - | linker |
| Lys 109 | - | linker |
| Val 110 | - | linker |
| Leu 111 | - | linker |
| Ala 112 | - | linker |
| Asn 113 | - | linker |
| PDB | External Database | Details |
|---|---|---|
| Cys 160 | Thr 47 | conflict |
| PDB | External Database | Details |
|---|---|---|
| Met 0 | - | initiating methionine |
| PDB | External Database | Details |
|---|---|---|
| Met 0 | - | initiating methionine |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 20 |
| Total formula weight | 382315.8 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 382.4 | |
| All* | Total formula weight | 382698.2 |
