9W1B

Cryo-EM structure of a Fungal XPR1 with InsP6

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, E)	Protein SYG1 homolog	polymer	707	82913.3	2	UniProt (Q9UU86)	Schizosaccharomyces pombe 972h-	SpXPR1 with InsP6
2	AA, BA, C, CA, D... (E, A)	(2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate	non-polymer		760.1	18	Chemie (POV)
3	G, Y (A, E)	(2R)-3-{[(S)-(2-aminoethoxy)(hydroxy)phosphoryl]oxy}-2-(tetradecanoyloxy)propyl octadecanoate	non-polymer		692.0	2	Chemie (8PE)
4	L, Q, R, T (A, E)	INOSITOL HEXAKISPHOSPHATE	non-polymer		660.0	4	Chemie (IHP)
5	DA, EA, FA, M, N... (E, A)	PHOSPHATE ION	non-polymer		95.0	6	Chemie (PO4)

Sequence modifications

A, E: 2 - 682 (UniProt: Q9UU86)

PDB	External Database	Details
Met -24	-	initiating methionine
Asp -23	-	expression tag
Tyr -22	-	expression tag
Lys -21	-	expression tag
Asp -20	-	expression tag
Asp -19	-	expression tag
Asp -18	-	expression tag
Asp -17	-	expression tag
Lys -16	-	expression tag
Gly -15	-	expression tag
Gly -14	-	expression tag
Ser -13	-	expression tag
Gly -12	-	expression tag
Ser -11	-	expression tag
Gly -10	-	expression tag
Gly -9	-	expression tag
Ser -8	-	expression tag
Gly -7	-	expression tag
Ser -6	-	expression tag
Gly -5	-	expression tag
Ser -4	-	expression tag
Ser -3	-	expression tag
Gly -2	-	expression tag
Ser -1	-	expression tag
Thr 0	-	expression tag
Gly 1	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	165826.6
Non-Polymers*	Number of molecules	30
	Total formula weight	18275.3
All*	Total formula weight	184101.8

*Water molecules are not included.