9VVV
Crystal structure of USP15 catalytic domain in complex with Ub-PA
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (A, B) | Ubiquitin carboxyl-terminal hydrolase 15 | polymer | 347 | 39558.8 | 2 | UniProt (Q9Y4E8) Pfam (PF00443) | Homo sapiens (human) | Deubiquitinating enzyme 15,Ubiquitin thioesterase 15,Ubiquitin-specific-processing protease 15,Unph-2,Unph4 |
| 2 | B, D (C, D) | Polyubiquitin-C | polymer | 76 | 8558.9 | 2 | UniProt (P0CG48) Pfam (PF00240) | Homo sapiens (human) | |
| 3 | E, G (A, B) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) PubChem (32051) | |||
| 4 | F (A) | IMIDAZOLE | non-polymer | 69.1 | 1 | Chemie (IMD) | |||
| 5 | H, I, J, K (A, C, B, D) | water | water | 18.0 | 149 | Chemie (HOH) |
Sequence modifications
A, B: 284 - 468 (UniProt: Q9Y4E8)
A, B: 786 - 941 (UniProt: Q9Y4E8)
C, D: 1 - 76 (UniProt: P0CG48)
| PDB | External Database | Details |
|---|---|---|
| Ser 283 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Ala 469 | - | linker |
| Ser 470 | - | linker |
| Thr 783 | - | linker |
| Ser 784 | - | linker |
| Lys 785 | - | linker |
| PDB | External Database | Details |
|---|---|---|
| Aye 76 | Gly 76 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 96235.3 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 199.9 | |
| All* | Total formula weight | 96435.2 |
