9VVV
Crystal structure of USP15 catalytic domain in complex with Ub-PA
Functional Information from PROSITE/UniProt
| site_id | PS00299 |
| Number of Residues | 26 |
| Details | UBIQUITIN_1 Ubiquitin domain signature. KakIqDkegIPpdqQrLIFaGkqleD |
| Chain | Residue | Details |
| C | LYS27-ASP52 |
| site_id | PS00972 |
| Number of Residues | 16 |
| Details | USP_1 Ubiquitin specific protease (USP) domain signature 1. GLsnlGNtCFMNSaIQ |
| Chain | Residue | Details |
| A | GLY290-GLN305 |
| site_id | PS00973 |
| Number of Residues | 18 |
| Details | USP_2 Ubiquitin specific protease (USP) domain signature 2. YnLiAVsnHyGgmgg..GHY |
| Chain | Residue | Details |
| A | TYR875-TYR892 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Nucleophile","evidences":[{"source":"PROSITE-ProRule","id":"PRU01035","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"19553310","evidenceCode":"ECO:0000305"},{"source":"PubMed","id":"21947082","evidenceCode":"ECO:0000305"},{"source":"PubMed","id":"22344298","evidenceCode":"ECO:0000305"},{"source":"PubMed","id":"24852371","evidenceCode":"ECO:0000305"},{"source":"PubMed","id":"27368102","evidenceCode":"ECO:0000305"},{"source":"PubMed","id":"33093067","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Proton acceptor","evidences":[{"source":"PROSITE-ProRule","id":"PRU10092","evidenceCode":"ECO:0000255"},{"source":"PROSITE-ProRule","id":"PRU10093","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
