9VPG

Cryo-EM structure of human urate transporter GLUT9 bound to a selective inhibitor SG4

This is a non-PDB format compatible entry.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Solute carrier family 2, facilitated glucose transporter member 9	polymer	582	63215.1	1	UniProt (Q9NRM0) Pfam (PF00083)	Homo sapiens (human)	Glucose transporter type 9,GLUT-9,Urate transporter
2	B (A)	(~{E})-3-[2-(4-hydroxyphenyl)-4-oxidanylidene-3~{H}-quinazolin-8-yl]-~{N}-propan-2-yl-prop-2-enamide	non-polymer		349.4	1	Chemie (A1ETZ)

Sequence modifications

A: 2 - 540 (UniProt: Q9NRM0)

PDB	External Database	Details
Met -41	-	initiating methionine
Ala -40	-	expression tag
Ser -39	-	expression tag
Trp -38	-	expression tag
Ser -37	-	expression tag
His -36	-	expression tag
Pro -35	-	expression tag
Gln -34	-	expression tag
Phe -33	-	expression tag
Glu -32	-	expression tag
Lys -31	-	expression tag
Gly -30	-	expression tag
Gly -29	-	expression tag
Gly -28	-	expression tag
Ala -27	-	expression tag
Arg -26	-	expression tag
Gly -25	-	expression tag
Gly -24	-	expression tag
Ser -23	-	expression tag
Gly -22	-	expression tag
Gly -21	-	expression tag
Gly -20	-	expression tag
Ser -19	-	expression tag
Trp -18	-	expression tag
Ser -17	-	expression tag
His -16	-	expression tag
Pro -15	-	expression tag
Gln -14	-	expression tag
Phe -13	-	expression tag
Glu -12	-	expression tag
Lys -11	-	expression tag
Gly -10	-	expression tag
Phe -9	-	expression tag
Asp -8	-	expression tag
Tyr -7	-	expression tag
Lys -6	-	expression tag
Asp -5	-	expression tag
Asp -4	-	expression tag
Asp -3	-	expression tag
Asp -2	-	expression tag
Lys -1	-	expression tag
Gly 0	-	expression tag
Thr 1	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	63215.1
Non-Polymers*	Number of molecules	1
	Total formula weight	349.4
All*	Total formula weight	63564.5

*Water molecules are not included.