9VP7

Glucose-6-phosphate dehydrogenase from Leishmania donovani in complex with pseudo substrate

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Glucose-6-phosphate 1-dehydrogenase	polymer	596	66933.8	2	UniProt (A2CIK6) Pfam (PF00479) Pfam (PF02781)	Leishmania donovani
2	C, E, G, J (A, B)	DI(HYDROXYETHYL)ETHER	non-polymer		106.1	4	Chemie (PEG)
3	D, K, L, M, N (A, B)	1,2-ETHANEDIOL	non-polymer		62.1	5	Chemie (EDO)
4	F (A)	2-amino-2-deoxy-6-O-phosphono-alpha-D-glucopyranose	non-polymer		259.2	1	Chemie (GLP)
5	H, I (B)	GLYCEROL	non-polymer		92.1	2	Chemie (GOL)
6	O, P (A, B)	water	water		18.0	724	Chemie (HOH)

Sequence modifications

A, B: 1 - 562 (UniProt: A2CIK6)

PDB	External Database	Details
Met -33	-	initiating methionine
Gly -32	-	expression tag
Ser -31	-	expression tag
Ser -30	-	expression tag
His -29	-	expression tag
His -28	-	expression tag
His -27	-	expression tag
His -26	-	expression tag
His -25	-	expression tag
His -24	-	expression tag
Ser -23	-	expression tag
Ser -22	-	expression tag
Gly -21	-	expression tag
Leu -20	-	expression tag
Val -19	-	expression tag
Pro -18	-	expression tag
Arg -17	-	expression tag
Gly -16	-	expression tag
Ser -15	-	expression tag
His -14	-	expression tag
Met -13	-	expression tag
Ala -12	-	expression tag
Ser -11	-	expression tag
Met -10	-	expression tag
Thr -9	-	expression tag
Gly -8	-	expression tag
Gly -7	-	expression tag
Gln -6	-	expression tag
Gln -5	-	expression tag
Met -4	-	expression tag
Gly -3	-	expression tag
Arg -2	-	expression tag
Gly -1	-	expression tag
Ser 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	133867.6
Non-Polymers*	Number of molecules	12
	Total formula weight	1178.2
All*	Total formula weight	135045.8

*Water molecules are not included.