9VP6

Glucose-6-phosphate dehydrogenase from Leishmania donovani in complex with substrate

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Glucose-6-phosphate 1-dehydrogenase	polymer	596	66933.8	2	UniProt (A2CIK6) Pfam (PF00479) Pfam (PF02781)	Leishmania donovani
2	C (A)	6-O-phosphono-beta-D-glucopyranose	non-polymer		260.1	1	Chemie (BG6)
3	D, I (A, B)	GLYCEROL	non-polymer		92.1	2	Chemie (GOL)
4	E, F, G, J (A, B)	1,2-ETHANEDIOL	non-polymer		62.1	4	Chemie (EDO)
5	H (B)	DI(HYDROXYETHYL)ETHER	non-polymer		106.1	1	Chemie (PEG)
6	K, L (A, B)	water	water		18.0	573	Chemie (HOH)

Sequence modifications

A, B: 1 - 562 (UniProt: A2CIK6)

PDB	External Database	Details
Met -33	-	initiating methionine
Gly -32	-	expression tag
Ser -31	-	expression tag
Ser -30	-	expression tag
His -29	-	expression tag
His -28	-	expression tag
His -27	-	expression tag
His -26	-	expression tag
His -25	-	expression tag
His -24	-	expression tag
Ser -23	-	expression tag
Ser -22	-	expression tag
Gly -21	-	expression tag
Leu -20	-	expression tag
Val -19	-	expression tag
Pro -18	-	expression tag
Arg -17	-	expression tag
Gly -16	-	expression tag
Ser -15	-	expression tag
His -14	-	expression tag
Met -13	-	expression tag
Ala -12	-	expression tag
Ser -11	-	expression tag
Met -10	-	expression tag
Thr -9	-	expression tag
Gly -8	-	expression tag
Gly -7	-	expression tag
Gln -6	-	expression tag
Gln -5	-	expression tag
Met -4	-	expression tag
Gly -3	-	expression tag
Arg -2	-	expression tag
Gly -1	-	expression tag
Ser 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	133867.6
Non-Polymers*	Number of molecules	8
	Total formula weight	798.7
All*	Total formula weight	134666.3

*Water molecules are not included.