9VN5

Structure of WDR5 in complex with MBD3C R43K

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C (A, B)	WD repeat-containing protein 5	polymer	315	34646.3	2	UniProt (P61964) Pfam (PF25175)	Homo sapiens (human)	BMP2-induced 3-kb gene protein
2	B, D (C, D)	Methyl-CpG binding domain protein 3	polymer	10	1037.2	2	UniProt (D3YTR4)	Mus musculus (house mouse)
3	E, F, G, H (A, C, B, D)	water	water		18.0	210	Chemie (HOH)

Sequence modifications

A, B: 24 - 334 (UniProt: P61964)

PDB	External Database	Details
Gly 20	-	expression tag
Ser 21	-	expression tag
His 22	-	expression tag
Met 23	-	expression tag

C, D: 40 - 49 (UniProt: D3YTR4)

PDB	External Database	Details
Lys 43	Arg 79	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	71367.1
All*	Total formula weight	71367.1

*Water molecules are not included.