9VED
The cryo-EM structure of mouse Piezo1-MDFI complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, C, B) | Piezo-type mechanosensitive ion channel component 1,Green fluorescent protein | polymer | 2815 | 322403.8 | 3 | UniProt (E2JF22) UniProt (P42212) | Mus musculus (house mouse) | Protein FAM38A |
| 2 | D, E, F (F, D, E) | Isoform I-mfA of MyoD family inhibitor | polymer | 269 | 27539.6 | 3 | UniProt (P70331) | Mus musculus (house mouse) | Myogenic repressor I-mf |
Sequence modifications
A, C, B: 1 - 2547 (UniProt: E2JF22)
A, C, B: 2565 - 2801 (UniProt: P42212)
F, D, E: 1 - 246 (UniProt: P70331)
| PDB | External Database | Details |
|---|---|---|
| Ser 2548 | - | linker |
| Asn 2549 | - | linker |
| Ser 2550 | - | linker |
| Leu 2551 | - | linker |
| Glu 2552 | - | linker |
| Val 2553 | - | linker |
| Leu 2554 | - | linker |
| Phe 2555 | - | linker |
| Gln 2556 | - | linker |
| Gly 2557 | - | linker |
| Pro 2558 | - | linker |
| Thr 2559 | - | linker |
| Ala 2560 | - | linker |
| Ala 2561 | - | linker |
| Ala 2562 | - | linker |
| Ala 2563 | - | linker |
| Val 2564 | - | linker |
| PDB | External Database | Details |
|---|---|---|
| Leu 2627 | Phe 64 | conflict |
| Thr 2628 | Ser 65 | conflict |
| Lys 2769 | Ala 206 | conflict |
| Leu 2794 | His 231 | conflict |
| Ser 2802 | - | expression tag |
| Gly 2803 | - | expression tag |
| Gly 2804 | - | expression tag |
| Gly 2805 | - | expression tag |
| His 2806 | - | expression tag |
| His 2807 | - | expression tag |
| His 2808 | - | expression tag |
| His 2809 | - | expression tag |
| His 2810 | - | expression tag |
| His 2811 | - | expression tag |
| His 2812 | - | expression tag |
| His 2813 | - | expression tag |
| His 2814 | - | expression tag |
| His 2815 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Met -22 | - | initiating methionine |
| Asp -21 | - | expression tag |
| Tyr -20 | - | expression tag |
| Lys -19 | - | expression tag |
| Asp -18 | - | expression tag |
| Asp -17 | - | expression tag |
| Asp -16 | - | expression tag |
| Asp -15 | - | expression tag |
| Lys -14 | - | expression tag |
| Gly -13 | - | expression tag |
| Gly -12 | - | expression tag |
| Gly -11 | - | expression tag |
| Gly -10 | - | expression tag |
| Ser -9 | - | expression tag |
| Ser -8 | - | expression tag |
| Thr -7 | - | expression tag |
| Thr -6 | - | expression tag |
| Asn -5 | - | expression tag |
| Gly -4 | - | expression tag |
| Ser -3 | - | expression tag |
| Ser -2 | - | expression tag |
| Ala -1 | - | expression tag |
| Thr 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 1049830.2 | |
| All* | Total formula weight | 1049830.2 |
