9VEC
structure of human KCNQ1-KCNE1-CaM complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, D, E, F (K, B, E, H) | Calmodulin-1 | polymer | 149 | 16852.5 | 4 | UniProt (P0DP23) Pfam (PF13499) | Homo sapiens (human) | |
| 2 | B, G, H, I (I, C, F, L) | Potassium voltage-gated channel subfamily E member 1 | polymer | 129 | 14664.7 | 4 | UniProt (P15382) Pfam (PF02060) | Homo sapiens (human) | Delayed rectifier potassium channel subunit IsK,IKs producing slow voltage-gated potassium channel subunit beta Mink,Minimal potassium channel,MinK |
| 3 | C, J, K, L (J, A, D, G) | Potassium voltage-gated channel subfamily KQT member 1 | polymer | 546 | 62076.3 | 4 | UniProt (P51787) Pfam (PF00520) Pfam (PF07885) Pfam (PF03520) | Homo sapiens (human) | IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1,KQT-like 1,Voltage-gated potassium channel subunit Kv7.1 |
| 4 | M, N, O, P, Q... (K, B, E, H) | CALCIUM ION | non-polymer | 40.1 | 8 | Chemie (CA) |
Sequence modifications
I, C, F, L: 1 - 129 (UniProt: P15382)
J, A, D, G: 76 - 620 (UniProt: P51787)
| PDB | External Database | Details |
|---|---|---|
| Cys 41 | Lys 41 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Met 75 | - | initiating methionine |
| Cys 145 | Ile 145 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 12 |
| Total formula weight | 374374.0 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 320.6 | |
| All* | Total formula weight | 374694.6 |
