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9VCK

Cryo-EM structure of SARS-CoV-2 nsp10/nsp14:RNA:SMP complex

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Non-structural protein 10polymer13113805.71UniProt (P0DTD1)
Pfam (PF09401)
Severe acute respiratory syndrome coronavirus 2nsp10,Growth factor-like peptide,GFL
2B
(B)
Guanine-N7 methyltransferase nsp14polymer52259316.81UniProt (P0DTD1)
Pfam (PF06471)
Severe acute respiratory syndrome coronavirus 2Non-structural protein 14,nsp14,Proofreading exoribonuclease nsp14,ExoN
3C
(P)
RNA (26-MER)polymer268217.91Severe acute respiratory syndrome coronavirus 2
4D
(T)
RNA (28-MER)polymer288967.31Severe acute respiratory syndrome coronavirus 2
5E, F, I, J, K
(A, B)
ZINC IONnon-polymer65.45Chemie (ZN)
6G, H
(B)
CALCIUM IONnon-polymer40.12Chemie (CA)
7L
(P)
[(2~{R},3~{R},4~{R},5~{R})-5-[2,4-bis(oxidanylidene)pyrimidin-1-yl]-4-fluoranyl-4-methyl-3-oxidanyl-oxolan-2-yl]methyl dihydrogen phosphatenon-polymer340.21Chemie (K5X)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight90307.8
Non-Polymers*Number of molecules8
Total formula weight747.4
All*Total formula weight91055.2
*Water molecules are not included.

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PDB entries from 2025-07-23

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