9V3S

Nav1.5 in complex with quinidine-azo

This is a non-PDB format compatible entry.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Sodium channel protein type 5 subunit alpha	polymer	1618	184033.4	1	UniProt (Q14524)	Homo sapiens (human)	Sodium channel protein cardiac muscle subunit alpha,Sodium channel protein type V subunit alpha,Voltage-gated sodium channel subunit alpha Nav1.5,hH1
2	B, C, D, E, F... (A)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	9	Chemie (NAG)
3	K (A)	(~{S})-[(1~{S},2~{R},4~{S},5~{R})-5-ethenyl-1-azabicyclo[2.2.2]octan-2-yl]-[6-methoxy-3-[4-(2-phenylhydrazinyl)phenyl]quinolin-4-yl]methanol	non-polymer		506.6	1	Chemie (A1EQU)
4	L (A)	SODIUM ION	non-polymer		23.0	1	Chemie (NA) PubChem (923)

Sequence modifications

A: 1 - 657 (UniProt: Q14524)

PDB	External Database	Details
Met -42	-	initiating methionine
Ala -41	-	expression tag
Ser -40	-	expression tag
Trp -39	-	expression tag
Ser -38	-	expression tag
His -37	-	expression tag
Pro -36	-	expression tag
Gln -35	-	expression tag
Phe -34	-	expression tag
Glu -33	-	expression tag
Lys -32	-	expression tag
Gly -31	-	expression tag
Gly -30	-	expression tag
Gly -29	-	expression tag
Ala -28	-	expression tag
Arg -27	-	expression tag
Gly -26	-	expression tag
Gly -25	-	expression tag
Ser -24	-	expression tag
Gly -23	-	expression tag
Gly -22	-	expression tag
Gly -21	-	expression tag
Ser -20	-	expression tag
Trp -19	-	expression tag
Ser -18	-	expression tag
His -17	-	expression tag
Pro -16	-	expression tag
Gln -15	-	expression tag
Phe -14	-	expression tag
Glu -13	-	expression tag
Lys -12	-	expression tag
Gly -11	-	expression tag
Phe -10	-	expression tag
Asp -9	-	expression tag
Tyr -8	-	expression tag
Lys -7	-	expression tag
Asp -6	-	expression tag
Asp -5	-	expression tag
Asp -4	-	expression tag
Asp -3	-	expression tag
Lys -2	-	expression tag
Gly -1	-	expression tag
Thr 0	-	expression tag

A: 658 - 1187 (UniProt: Q14524)
A: 1188 - 1894 (UniProt: Q14524)

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	184033.4
Non-Polymers*	Number of molecules	11
	Total formula weight	2520.5
All*	Total formula weight	186553.9

*Water molecules are not included.