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9V0J

Cryo-EM structure of GATOR1-KICSTOR complex

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
GATOR1 complex protein NPRL2polymer38043711.41UniProt (Q8WTW4)
Pfam (PF06218)
Homo sapiens (human)Gene 21 protein,G21 protein,Nitrogen permease regulator 2-like protein,NPR2-like protein,Tumor suppressor candidate 4
2B
(B)
GATOR1 complex protein NPRL3polymer56963680.81UniProt (Q12980)
Pfam (PF03666)
Pfam (PF24064)
Homo sapiens (human)-14 gene protein,Alpha-globin regulatory element-containing gene protein,Nitrogen permease regulator 3-like protein,Protein CGTHBA
3C
(C)
GATOR1 complex protein DEPDC5polymer1603181478.01UniProt (O75140)
Pfam (PF23013)
Pfam (PF12257)
Pfam (PF00610)
Pfam (PF19418)
Homo sapiens (human)DEP domain-containing protein 5
4D
(D)
KICSTOR complex protein SZT2polymer3432378453.41UniProt (Q5T011)Homo sapiens (human)Seizure threshold 2 protein homolog
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight667323.7
All*Total formula weight667323.7
*Water molecules are not included.

251422

PDB entries from 2026-04-01

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