9UX3
Cryo-EM structure of the human P2X2/3 heteromer receptor bound to AF-219
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | P2X purinoceptor 3 | polymer | 364 | 40900.1 | 1 | UniProt (P56373) Pfam (PF00864) | Homo sapiens (human) | P2X3,ATP receptor,Purinergic receptor |
| 2 | B, C (B, C) | P2X purinoceptor 2 | polymer | 471 | 51815.0 | 2 | UniProt (Q9UBL9) Pfam (PF00864) | Homo sapiens (human) | P2X2,ATP receptor,Purinergic receptor |
| 3 | D, E, F, H, I... (A, B, C) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 7 | Chemie (NAG) | |||
| 4 | G, J, K (A, B, C) | ADENOSINE-5'-TRIPHOSPHATE | non-polymer | 507.2 | 3 | Chemie (ATP) | |||
| 5 | L (C) | 5-[2,4-bis(azanyl)pyrimidin-5-yl]oxy-2-methoxy-4-propan-2-yl-benzenesulfonamide | non-polymer | 353.4 | 1 | Chemie (AF9) PubChem (24764487) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 144530.1 | |
| Non-Polymers* | Number of molecules | 11 |
| Total formula weight | 3423.4 | |
| All* | Total formula weight | 147953.5 |
