9UTC

The VFT domains of human sweet taste receptor TAS1R2 and TAS1R3 in the sucralose-bound state

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Taste receptor type 1 member 2,Taste receptor type 1 member 2,Engineered red fluorescent protein mScarlet3	polymer	1078	122191.2	1	UniProt (Q8TE23)	Homo sapiens (human)	G-protein coupled receptor 71,Sweet taste receptor T1R2
2	B (B)	Taste receptor type 1 member 3,mNeonGreen	polymer	1130	124906.6	1	UniProt (Q7RTX0) UniProt (A0A1S4NYF2)	Homo sapiens (human)	Sweet taste receptor T1R3
3	C (C)	4-chloro-4-deoxy-alpha-D-galactopyranose-(1-2)-1,6-dichloro-1,6-dideoxy-beta-D-fructofuranose	branched		397.6	1	BIRD (PRD_900090)

Sequence modifications

A: 26 - 839 (UniProt: Q8TE23)

PDB	External Database	Details
Met -3	-	initiating methionine
Lys -2	-	expression tag
Thr -1	-	expression tag
Ile 0	-	expression tag
Ile 1	-	expression tag
Ala 2	-	expression tag
Leu 3	-	expression tag
Ser 4	-	expression tag
Tyr 5	-	expression tag
Ile 6	-	expression tag
Phe 7	-	expression tag
Cys 8	-	expression tag
Leu 9	-	expression tag
Val 10	-	expression tag
Phe 11	-	expression tag
Ala 12	-	expression tag
Gly 13	-	expression tag
Ser 14	-	expression tag
Asp 15	-	expression tag
Tyr 16	-	expression tag
Lys 17	-	expression tag
Asp 18	-	expression tag
Asp 19	-	expression tag
Asp 20	-	expression tag
Asp 21	-	expression tag
Lys 22	-	expression tag
Gly 23	-	expression tag
Ser 24	-	expression tag
Ala 25	-	expression tag

A: 840 - 1074 (PDB: 9UTC)
B: 21 - 852 (UniProt: Q7RTX0)

PDB	External Database	Details
Met -7	-	initiating methionine
Lys -6	-	expression tag
Thr -5	-	expression tag
Ile -4	-	expression tag
Ile -3	-	expression tag
Ala -2	-	expression tag
Leu -1	-	expression tag
Ser 0	-	expression tag
Tyr 1	-	expression tag
Ile 2	-	expression tag
Phe 3	-	expression tag
Cys 4	-	expression tag
Leu 5	-	expression tag
Val 6	-	expression tag
Phe 7	-	expression tag
Ala 8	-	expression tag
Gly 9	-	expression tag
Ser 10	-	expression tag
Asp 11	-	expression tag
Tyr 12	-	expression tag
Lys 13	-	expression tag
Asp 14	-	expression tag
Asp 15	-	expression tag
Asp 16	-	expression tag
Asp 17	-	expression tag
Lys 18	-	expression tag
Gly 19	-	expression tag
Ser 20	-	expression tag
Gly 853	-	linker
Ser 854	-	linker
Ser 855	-	linker
Gly 856	-	linker
Leu 857	-	linker
Glu 858	-	linker
Val 859	-	linker
Leu 860	-	linker
Phe 861	-	linker
Gln 862	-	linker
Gly 863	-	linker
Pro 864	-	linker
Ser 865	-	linker
Gly 866	-	linker
Gly 867	-	linker

B: 868 - 1102 (UniProt: A0A1S4NYF2)

PDB	External Database	Details
Gly 1103	-	expression tag
Ser 1104	-	expression tag
Glu 1105	-	expression tag
Asn 1106	-	expression tag
Leu 1107	-	expression tag
Tyr 1108	-	expression tag
Phe 1109	-	expression tag
Gln 1110	-	expression tag
Ser 1111	-	expression tag
Ser 1112	-	expression tag
Gly 1113	-	expression tag
His 1114	-	expression tag
His 1115	-	expression tag
His 1116	-	expression tag
His 1117	-	expression tag
His 1118	-	expression tag
His 1119	-	expression tag
His 1120	-	expression tag
His 1121	-	expression tag
His 1122	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	247097.8
Branched	Number of molecules	1
	Total formula weight	397.6
All*	Total formula weight	247495.5

*Water molecules are not included.