9UGP
Crystal structure of MCL-1 in complex with HRK BH3
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Induced myeloid leukemia cell differentiation protein Mcl-1 | polymer | 154 | 17669.2 | 1 | UniProt (Q07820) Pfam (PF00452) | Homo sapiens (Human) | Bcl-2-like protein 3,Bcl2-L-3,Bcl-2-related protein EAT/mcl1,mcl1/EAT |
| 2 | B (B) | Activator of apoptosis harakiri | polymer | 25 | 2816.2 | 1 | UniProt (O00198) | Homo sapiens | BH3-interacting domain-containing protein 3,Neuronal death protein DP5 |
| 3 | C, D (A, B) | water | water | 18.0 | 176 | Chemie (HOH) |
Sequence modifications
A: 171 - 322 (UniProt: Q07820)
| PDB | External Database | Details |
|---|---|---|
| Ser 169 | - | expression tag |
| Met 170 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 20485.4 | |
| All* | Total formula weight | 20485.4 |
