9UCO

Cryo-EM structure of ADGRE1-beta arrestin1-scFv30 complex

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, D (A, C)	Beta-arrestin-1	polymer	376	42177.2	2	UniProt (P17870)	Mus musculus (house mouse)	Arrestin beta-1,Arrestin-2
2	B, C, E, F (B, F, D, E)	scFv30	polymer	251	26986.7	4		Bos taurus
3	G, I (L, G)	Adhesion G protein-coupled receptor E1	polymer	15	1563.8	2	UniProt (Q61549)	Mus musculus (house mouse)	Cell surface glycoprotein F4/80,EGF-like module receptor 1,EGF-like module-containing mucin-like hormone receptor-like 1,EMR1 hormone receptor
4	H, J (R, H)	Adhesion G protein-coupled receptor E1	polymer	287	32333.8	2	UniProt (Q61549)	Mus musculus (house mouse)	Cell surface glycoprotein F4/80,EGF-like module receptor 1,EGF-like module-containing mucin-like hormone receptor-like 1,EMR1 hormone receptor

Sequence modifications

A, C: 1 - 376 (UniProt: P17870)

PDB	External Database	Details
Ala 59	Cys 59	conflict
Ser 125	Cys 125	conflict
Ile 140	Cys 140	conflict
Val 150	Cys 150	conflict
Glu 169	Arg 169	conflict
Val 242	Cys 242	conflict
Val 251	Cys 251	conflict
Ser 269	Cys 269	conflict
Ser 342	Asp 342	conflict

R, H: 645 - 931 (UniProt: Q61549)

PDB	External Database	Details
Trp 872	Tyr 872	conflict

Contents of the asymmetric unit

Polymers	Number of chains	10
	Total formula weight	260096.6
All*	Total formula weight	260096.6

*Water molecules are not included.