9U8B

Structure of THIK1 complexed with C101248

This is a non-PDB format compatible entry.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Potassium channel subfamily K member 13	polymer	424	47161.1	2	UniProt (Q9HB14) Pfam (PF07885)	Homo sapiens (human)	Tandem pore domain halothane-inhibited potassium channel 1,THIK-1
2	C, E (A, B)	ARACHIDONIC ACID	non-polymer		304.5	2	Chemie (ACD) PubChem (87131823) PubChem (87196993) PubChem (92449654) PubChem (122651992) PubChem (122652036) PubChem (122652077) PubChem (173636367) PubChem (173785266) PubChem (174059456) PubChem (175709969) PubChem (175736020) PubChem (175951410) PubChem (231) PubChem (122652008) PubChem (114670) PubChem (444899) PubChem (5312542) PubChem (12083498) PubChem (12096305) PubChem (12111897) PubChem (12183869) PubChem (12358407) PubChem (12358409) PubChem (12358410) PubChem (12358414) PubChem (12990988)
3	D (A)	4-[1-(pyridin-4-ylmethyl)benzimidazol-2-yl]-1,2,5-oxadiazol-3-amine	non-polymer		292.3	1	Chemie (A1ENQ)

Sequence modifications

A, B: 1 - 408 (UniProt: Q9HB14)

PDB	External Database	Details
Leu 409	-	expression tag
Glu 410	-	expression tag
Gly 411	-	expression tag
Gly 412	-	expression tag
Val 413	-	expression tag
Glu 414	-	expression tag
Gly 415	-	expression tag
Gly 416	-	expression tag
Val 417	-	expression tag
Glu 418	-	expression tag
Glu 419	-	expression tag
Asn 420	-	expression tag
Leu 421	-	expression tag
Tyr 422	-	expression tag
Phe 423	-	expression tag
Gln 424	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	94322.2
Non-Polymers*	Number of molecules	3
	Total formula weight	901.2
All*	Total formula weight	95223.5

*Water molecules are not included.