9U18
Crystal structure of the NKX2.1 homeodomain in complex with a 12-bp DNA duplex containing a CAAG motif
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, D (A, D) | CAAG-containing 12bp forward strand | polymer | 12 | 3677.4 | 2 | Homo sapiens | ||
| 2 | B (B) | 12bp reverse complementary | polymer | 11 | 3342.2 | 1 | Homo sapiens | ||
| 3 | C, F (C, F) | Homeobox protein Nkx-2.1 | polymer | 60 | 7546.8 | 2 | UniProt (P43699) Pfam (PF00046) | Homo sapiens (human) | Homeobox protein NK-2 homolog A,Thyroid nuclear factor 1,Thyroid transcription factor 1,TTF-1,Thyroid-specific enhancer-binding protein,T/EBP |
| 4 | E (E) | 12bp reverse complementary | polymer | 12 | 3661.4 | 1 | Homo sapiens | ||
| 5 | G, H, I, J, K... (A, B, C, D, E...) | water | water | 18.0 | 349 | Chemie (HOH) |
Sequence modifications
C, F: 161 - 219 (UniProt: P43699)
| PDB | External Database | Details |
|---|---|---|
| Gly 160 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 29452.1 | |
| All* | Total formula weight | 29452.1 |
