9TUY

PfRIPR EGF6 and 7 bound to monoclonal antibody MAD8-739

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C (A, C)	MAD8-739 scFv	polymer	288	29815.3	2		Homo sapiens
2	B, D (B, D)	Immunoglobulin gamma-1 heavy chain,Rh5-interacting protein	polymer	359	39875.9	2	UniProt (P0DOX5) UniProt (O97302)	Homo sapiens (human)	Immunoglobulin gamma-1 heavy chain NIE,PfRipr
3	E, F, G, H (A, B, C, D)	water	water		18.0	63	Chemie (HOH)

Sequence modifications

B, D: 487 - 698 (UniProt: P0DOX5)

PDB	External Database	Details
Met 468	-	initiating methionine
Gly 469	-	expression tag
Trp 470	-	expression tag
Ser 471	-	expression tag
Cys 472	-	expression tag
Ile 473	-	expression tag
Ile 474	-	expression tag
Leu 475	-	expression tag
Phe 476	-	expression tag
Leu 477	-	expression tag
Val 478	-	expression tag
Ala 479	-	expression tag
Thr 480	-	expression tag
Ala 481	-	expression tag
Thr 482	-	expression tag
Gly 483	-	expression tag
Val 484	-	expression tag
His 485	-	expression tag
Ser 486	-	expression tag
Asn 615	Ser 366	conflict
Asn 658	Tyr 409	conflict
Gly 699	-	linker
Gly 700	-	linker
Gly 701	-	linker
Gly 702	-	linker
Ser 703	-	linker
Gly 704	-	linker
Gly 705	-	linker
Gly 706	-	linker
Ser 707	-	linker
Glu 708	-	linker
Asn 709	-	linker
Leu 710	-	linker
Tyr 711	-	linker
Phe 712	-	linker
Gln 713	-	linker
Gly 714	-	linker
Ser 715	-	linker

B, D: 716 - 816 (UniProt: O97302)

PDB	External Database	Details
Gly 817	-	expression tag
Gly 818	-	expression tag
Thr 819	-	expression tag
Gly 820	-	expression tag
Gly 821	-	expression tag
Ser 822	-	expression tag
Glu 823	-	expression tag
Pro 824	-	expression tag
Glu 825	-	expression tag
Ala 826	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	139382.4
All*	Total formula weight	139382.4

*Water molecules are not included.