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9TH8

Cryo-EM structure of MCM2-7 DH bound to Sld3-Sld7, Cdc45 and DNA

This is a non-PDB format compatible entry.
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(O)
dsDNA (60-MER)polymer6018491.81Saccharomyces cerevisiae
2B
(S)
dsDNA (60-MER)polymer6018491.81Saccharomyces cerevisiae
3C, I
(B, 2)
DNA replication licensing factor MCM2polymer86898911.52UniProt (P29469)Saccharomyces cerevisiae (brewer's yeast)Minichromosome maintenance protein 2
4D, J
(C, 3)
DNA replication licensing factor MCM3polymer971107653.52UniProt (P24279)Saccharomyces cerevisiae (brewer's yeast)Minichromosome maintenance protein 3
5E, K
(D, 4)
DNA replication licensing factor MCM4polymer933105138.42UniProt (P30665)Saccharomyces cerevisiae (brewer's yeast)Cell division control protein 54
6F, L
(E, 5)
Minichromosome maintenance protein 5polymer77586505.72UniProt (P29496)Saccharomyces cerevisiae (brewer's yeast)Cell division control protein 46
7G, M
(F, 6)
DNA replication licensing factor MCM6polymer1017113110.22UniProt (P53091)Saccharomyces cerevisiae (brewer's yeast)Minichromosome maintenance protein 6
8H, N
(G, 7)
DNA replication licensing factor MCM7polymer84595049.92UniProt (P38132)Saccharomyces cerevisiae (brewer's yeast)Cell division control protein 47,Minichromosome maintenance protein 7
9O
(X)
DNA replication regulator SLD3polymer66877428.61UniProt (P53135)Saccharomyces cerevisiae (brewer's yeast)
10P
(Z)
Cell division control protein 45polymer65074324.81UniProt (Q08032)Saccharomyces cerevisiae (brewer's yeast)
11Q
(Y)
Mitochondrial morphogenesis protein SLD7polymer25729598.81UniProt (Q08457)Saccharomyces cerevisiae (brewer's yeast)Synthetic lethality with DPB11-24 mutation protein 7
12AA, CA, EA, HA, R...
(2, 3, 5, 7, B...)
ADENOSINE-5'-DIPHOSPHATEnon-polymer427.28Chemie (ADP)
13BA, DA, FA, GA, IA...
(2, 4, 5, 6, 7...)
ZINC IONnon-polymer65.410Chemie (ZN)
PubChem (32051)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains17
Total formula weight1431074.5
Non-Polymers*Number of molecules18
Total formula weight4071.7
All*Total formula weight1435146.2
*Water molecules are not included.

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PDB entries from 2026-08-26

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