9TF5
Structure of human wild-type signal regulatory protein alpha V2 variant (SIRPaV2) with zinc
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | Isoform 4 of Tyrosine-protein phosphatase non-receptor type substrate 1 | polymer | 119 | 12919.5 | 3 | UniProt (P78324) Pfam (PF07686) | Homo sapiens (human) | SHP substrate 1,SHPS-1,Brain Ig-like molecule with tyrosine-based activation motifs,Bit,CD172 antigen-like family member A,Inhibitory receptor SHPS-1,Macrophage fusion receptor,MyD-1 antigen,Signal-regulatory protein alpha-1,Sirp-alpha-1,Signal-regulatory protein alpha-2,Sirp-alpha-2,Signal-regulatory protein alpha-3,Sirp-alpha-3,p84 |
| 2 | D, E, F, G, H... (A, B, C) | ZINC ION | non-polymer | 65.4 | 7 | Chemie (ZN) | |||
| 3 | I, J (B) | SULFATE ION | non-polymer | 96.1 | 2 | Chemie (SO4) | |||
| 4 | M, N, O (A, B, C) | water | water | 18.0 | 323 | Chemie (HOH) |
Sequence modifications
A, B, C: 1 - 118 (UniProt: P78324)
| PDB | External Database | Details |
|---|---|---|
| Ser 0 | - | expression tag |
| Ser 14 | Leu 44 | variant |
| Ser 20 | Thr 50 | variant |
| Ile 22 | Thr 52 | variant |
| His 24 | Arg 54 | variant |
| Val 27 | Ala 57 | variant |
| Ala 45 | Gly 75 | variant |
| Glu 65 | Asp 95 | variant |
| Ser 66 | Leu 96 | variant |
| Glu 70 | Asn 100 | variant |
| Ser 77 | Arg 107 | variant |
| Ser 79 | Gly 109 | variant |
| Thr 101 | Val 131 | variant |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 38758.4 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 650.0 | |
| All* | Total formula weight | 39408.4 |
