9TDA
ERAP1 in complex with 1-[2-(5-bromo-7-fluoro-2-oxo-2,3-dihydro-1,3-benzothiazol-3-yl)acetamido]-4,4-difluorocyclohexane-1-carboxylic acid
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Endoplasmic reticulum aminopeptidase 1 | polymer | 922 | 105371.4 | 1 | UniProt (Q9NZ08) Pfam (PF17900) Pfam (PF01433) Pfam (PF11838) | Homo sapiens (human) | ARTS-1,Adipocyte-derived leucine aminopeptidase,A-LAP,Aminopeptidase PILS,Puromycin-insensitive leucyl-specific aminopeptidase,PILS-AP,Type 1 tumor necrosis factor receptor shedding aminopeptidase regulator |
| 2 | B (A) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) PubChem (32051) | |||
| 3 | C (A) | SUCCINIC ACID | non-polymer | 118.1 | 1 | Chemie (SIN) PubChem (1110) | |||
| 4 | D (A) | PHOSPHATE ION | non-polymer | 95.0 | 1 | Chemie (PO4) PubChem (1061) | |||
| 5 | E, F, G, H, I... (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 9 | Chemie (EDO) | |||
| 6 | N (A) | 1-[2-(5-bromanyl-7-fluoranyl-2-oxidanylidene-1,3-benzothiazol-3-yl)ethanoylamino]-4,4-bis(fluoranyl)cyclohexane-1-carboxylic acid | non-polymer | 467.3 | 1 | Chemie (A1JVE) | |||
| 7 | O (A) | water | water | 18.0 | 1138 | Chemie (HOH) |
Sequence modifications
A: 1 - 485 (UniProt: Q9NZ08)
A: 514 - 941 (UniProt: Q9NZ08)
| PDB | External Database | Details |
|---|---|---|
| Gln 70 | Asn 70 | conflict |
| Gln 154 | Asn 154 | conflict |
| Gln 414 | Asn 414 | conflict |
| PDB | External Database | Details |
|---|---|---|
| Gly 486 | - | linker |
| Ser 512 | - | linker |
| Gly 513 | - | linker |
| Arg 528 | Lys 528 | conflict |
| Gln 760 | Asn 760 | conflict |
| Glu 942 | - | expression tag |
| Asn 943 | - | expression tag |
| Leu 944 | - | expression tag |
| Tyr 945 | - | expression tag |
| Phe 946 | - | expression tag |
| Gln 947 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 105371.4 | |
| Non-Polymers* | Number of molecules | 13 |
| Total formula weight | 1304.3 | |
| All* | Total formula weight | 106675.8 |
