9T3S
Structure of human HER2 in complex with EPS226 Fab
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (H) | EPS226 Fab HC | polymer | 267 | 28701.9 | 1 | Homo sapiens | ||
| 2 | B (L) | EPS226 Fab LC | polymer | 216 | 22719.0 | 1 | Homo sapiens | ||
| 3 | C (A) | Receptor tyrosine-protein kinase erbB-2 | polymer | 636 | 70249.7 | 1 | UniProt (P04626) | Homo sapiens (human) | Metastatic lymph node gene 19 protein,MLN 19,Proto-oncogene Neu,Proto-oncogene c-ErbB-2,Tyrosine kinase-type cell surface receptor HER2,p185erbB2 |
Sequence modifications
A: 23 - 652 (UniProt: P04626)
| PDB | External Database | Details |
|---|---|---|
| His 653 | - | expression tag |
| His 654 | - | expression tag |
| His 655 | - | expression tag |
| His 656 | - | expression tag |
| His 657 | - | expression tag |
| His 658 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 121670.6 | |
| All* | Total formula weight | 121670.6 |
