9T33
Cryo-EM structure of homo-hexameric hLRRC8A double mutation W168L/L402W
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (A, B, C, D, E...) | Volume-regulated anion channel subunit LRRC8A | polymer | 811 | 94345.5 | 6 | UniProt (Q8IWT6) | Homo sapiens (human) | Leucine-rich repeat-containing protein 8A,HsLRRC8A,Swelling protein 1 |
Sequence modifications
A, B, C, D, E, F: 2 - 810 (UniProt: Q8IWT6)
| PDB | External Database | Details |
|---|---|---|
| Ser 1 | - | expression tag |
| Leu 168 | Trp 168 | engineered mutation |
| Trp 402 | Leu 402 | engineered mutation |
| Ala 811 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 566072.9 | |
| All* | Total formula weight | 566072.9 |
