9T2D
Jumonji domain-containing protein 2B with crystallization epitope mutations L916G:R917A:A918D
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Lysine-specific demethylase 4B | polymer | 132 | 14724.4 | 1 | UniProt (O94953) | Homo sapiens (human) | JmjC domain-containing histone demethylation protein 3B,Jumonji domain-containing protein 2B,[histone H3]-trimethyl-L-lysine(9) demethylase 4B |
| 2 | B, C, D, E, F... (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 6 | Chemie (EDO) | |||
| 3 | H, I (A) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 2 | Chemie (PEG) | |||
| 4 | J (A) | AMMONIUM ION | non-polymer | 18.0 | 1 | Chemie (NH4) | |||
| 5 | K (A) | water | water | 18.0 | 75 | Chemie (HOH) |
Sequence modifications
A: 3 - 132 (UniProt: O94953)
| PDB | External Database | Details |
|---|---|---|
| Ser 1 | - | expression tag |
| Met 2 | - | expression tag |
| Gly 4 | Leu 916 | engineered mutation |
| Ala 5 | Arg 917 | engineered mutation |
| Asp 6 | Ala 918 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 14724.4 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 602.7 | |
| All* | Total formula weight | 15327.1 |
