9T00
Crystal structure of prethrombin-2 with a peptide corresponding to the C-terminus of the heavy chain of factor Va
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (A, C) | Prothrombin | polymer | 314 | 36046.2 | 2 | UniProt (P00734) | Homo sapiens (human) | Coagulation factor II |
| 2 | B, D (B, D) | Coagulation factor V heavy chain | polymer | 24 | 2902.8 | 2 | UniProt (P12259) | Homo sapiens | |
| 3 | E, F (A, C) | water | water | 18.0 | 11 | Chemie (HOH) |
Sequence modifications
A, C: 267 - 579 (UniProt: P00734)
| PDB | External Database | Details |
|---|---|---|
| Met 266 | - | initiating methionine |
| Ala 525 | Ser 568 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 77897.9 | |
| All* | Total formula weight | 77897.9 |
