9SZW

Human carboxyhemoglobin bound to full-length Staphylococcus aureus IsdH - IsdH:Hbdim complex

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Hemoglobin subunit alpha	polymer	140	15051.2	1	UniProt (P69905) Pfam (PF00042)	Homo sapiens (human)	Alpha-globin,Hemoglobin alpha chain
2	B (B)	Hemoglobin subunit beta	polymer	145	15791.1	1	UniProt (P68871) Pfam (PF00042)	Homo sapiens (human)	Beta-globin,Hemoglobin beta chain
3	C (C)	Iron-regulated surface determinant protein H	polymer	616	70354.8	1	UniProt (Q8NW39)	Staphylococcus aureus	Haptoglobin receptor A,Staphylococcus aureus surface protein I
4	D, E (A, B)	PROTOPORPHYRIN IX CONTAINING FE	non-polymer		616.5	2	Chemie (HEM)

Sequence modifications

C: 86 - 665 (UniProt: Q8NW39)

PDB	External Database	Details
Met 66	-	initiating methionine
Gly 67	-	expression tag
Ser 68	-	expression tag
Ser 69	-	expression tag
His 70	-	expression tag
His 71	-	expression tag
His 72	-	expression tag
His 73	-	expression tag
His 74	-	expression tag
His 75	-	expression tag
Ser 76	-	expression tag
Ser 77	-	expression tag
Gly 78	-	expression tag
Leu 79	-	expression tag
Val 80	-	expression tag
Pro 81	-	expression tag
Arg 82	-	expression tag
Gly 83	-	expression tag
Ser 84	-	expression tag
His 85	-	expression tag
Glu 666	-	expression tag
Asn 667	-	expression tag
Leu 668	-	expression tag
Tyr 669	-	expression tag
Phe 670	-	expression tag
Gln 671	-	expression tag
Ser 672	-	expression tag
Ala 673	-	expression tag
Trp 674	-	expression tag
Ser 675	-	expression tag
His 676	-	expression tag
Pro 677	-	expression tag
Gln 678	-	expression tag
Phe 679	-	expression tag
Glu 680	-	expression tag
Lys 681	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	101197.1
Non-Polymers*	Number of molecules	2
	Total formula weight	1233.0
All*	Total formula weight	102430.0

*Water molecules are not included.