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9SWN

Cryo-EM structure of yeast telomerase holoenzyme

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(C)
Telomere replication protein EST3polymer18120577.51UniProt (Q03096)Saccharomyces cerevisiae (brewer's yeast)Ever shorter telomeres protein 3
2B
(E)
Ribonucleases P/MRP protein subunit POP6polymer15818235.01UniProt (P53218)Saccharomyces cerevisiae (brewer's yeast)RNA-processing protein POP6,RNases P/MRP 18.2 kDa subunit
3C
(G)
Telomere elongation protein EST1polymer69981920.91UniProt (P17214)Saccharomyces cerevisiae (brewer's yeast)Ever shorter telomeres protein 1
4D
(F)
Ribonucleases P/MRP protein subunit POP7polymer14015844.31UniProt (P38291)Saccharomyces cerevisiae (brewer's yeast)RNA-processing protein POP7,RNases P/MRP 15.8 kDa subunit
5E
(D)
Ribonucleases P/MRP protein subunit POP1polymer875100559.61UniProt (P41812)Saccharomyces cerevisiae (brewer's yeast)RNA-processing protein POP1,RNases P/MRP 100.4 kDa subunit
6F
(B)
TLC1 RNApolymer1157370246.41GenBank (U14595.1)Saccharomyces cerevisiae (brewer's yeast)
7G
(A)
Telomerase reverse transcriptasepolymer884102768.11UniProt (Q06163)Saccharomyces cerevisiae (brewer's yeast)Telomerase catalytic subunit
8H, J
(D, A)
ZINC IONnon-polymer65.42Chemie (ZN)
9I
(A)
MAGNESIUM IONnon-polymer24.31Chemie (MG)
PubChem (888)
10K, L
(C, B)
waterwater18.02Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains7
Total formula weight710151.7
Non-Polymers*Number of molecules3
Total formula weight155.1
All*Total formula weight710306.9
*Water molecules are not included.

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PDB entries from 2026-04-08

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