9SWN
Cryo-EM structure of yeast telomerase holoenzyme
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (C) | Telomere replication protein EST3 | polymer | 181 | 20577.5 | 1 | UniProt (Q03096) Pfam (PF10341) | Saccharomyces cerevisiae (brewer's yeast) | Ever shorter telomeres protein 3 |
| 2 | B (E) | Ribonucleases P/MRP protein subunit POP6 | polymer | 158 | 18235.0 | 1 | UniProt (P53218) Pfam (PF01918) | Saccharomyces cerevisiae (brewer's yeast) | RNA-processing protein POP6,RNases P/MRP 18.2 kDa subunit |
| 3 | C (G) | Telomere elongation protein EST1 | polymer | 699 | 81920.9 | 1 | UniProt (P17214) Pfam (PF10374) Pfam (PF10373) | Saccharomyces cerevisiae (brewer's yeast) | Ever shorter telomeres protein 1 |
| 4 | D (F) | Ribonucleases P/MRP protein subunit POP7 | polymer | 140 | 15844.3 | 1 | UniProt (P38291) Pfam (PF12328) | Saccharomyces cerevisiae (brewer's yeast) | RNA-processing protein POP7,RNases P/MRP 15.8 kDa subunit |
| 5 | E (D) | Ribonucleases P/MRP protein subunit POP1 | polymer | 875 | 100559.6 | 1 | UniProt (P41812) Pfam (PF06978) Pfam (PF08170) Pfam (PF22770) | Saccharomyces cerevisiae (brewer's yeast) | RNA-processing protein POP1,RNases P/MRP 100.4 kDa subunit |
| 6 | F (B) | TLC1 RNA | polymer | 1157 | 370246.4 | 1 | GenBank (U14595.1) | Saccharomyces cerevisiae (brewer's yeast) | |
| 7 | G (A) | Telomerase reverse transcriptase | polymer | 884 | 102768.1 | 1 | UniProt (Q06163) Pfam (PF12009) | Saccharomyces cerevisiae (brewer's yeast) | Telomerase catalytic subunit |
| 8 | H, J (D, A) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) PubChem (32051) | |||
| 9 | I (A) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) PubChem (888) | |||
| 10 | K, L (C, B) | water | water | 18.0 | 2 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 7 |
| Total formula weight | 710151.7 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 155.1 | |
| All* | Total formula weight | 710306.9 |
